In my organization, we use Veeam for both online and on-premises backups for around 200 sites across the globe. All our secondary cloud backups are performed using Amazon Web Services. We first started with version 8.4 which came out about six years ago and we're now currently using version 10.0, with plans to upgrade all our backup infrastructure to version 11.0 in the near future.
For each site, we have independent and standalone VBRs and every one of them is managed through the Enterprise Manager's console. For our reporting needs, we use Veeam ONE and a SolarWinds integration.